Drug Interactions:
Colchicine

Although primarily used on a short-term basis to treat attacks of gout, colchicine is increasingly being prescribed for longer periods as a gout preventive. This practice may heighten the chance of developing the nutritional deficiency discussed here.

Vitamin B12

Supplementation Possibly Helpful

Colchicine can impair intestinal absorption of vitamin B₁₂, so taking a B₁₂ supplement during extended colchicine therapy may be warranted.¹

Last reviewed March 2002 by Medical Review Board

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