Dementia

Dementia is the progressive loss of various mental functions, including:
  • Memory
  • Ability to learn
  • Judgment
  • Ability to reason
Most people with dementia are eventually unable to care for themselves.

Causes

Alzheimers disease is the most common cause of dementia. Other conditions that may be associated with Dementia include:
  • Brain damage after multiple small strokes
  • Alcoholism
  • AIDS
  • Multiple sclerosis
  • Huntington's disease
  • Parkinson's disease
  • Creutzfeldt-Jacob disease
  • Lewy body disease
  • Pick's disease
  • Medications, including:
    • Benzodiazepines
    • Tricyclic antidepressants
    • Antipsychotic medications
    • Monoamine oxidase inhibitors
    • Barbiturates
    • Cough preparations
    • Digitalis
    • Anticholinergic medications
  • Conditions that deprive the brain of oxygen including severe heart and lung disease
  • Liver disease
  • Severe, long-term abnormalities of blood electrolytes, including:
    • Excess calcium
    • Excess sodium
    • Low sodium
  • Encephalitis
  • Untreated syphilis
  • Toxic levels of aluminum (as can sometimes occur in dialysis patients)

Risk Factors

A risk factor is something that increases your chance of getting a disease or condition.
  • Age: 85 and older
  • Family members with dementing illness
  • Down syndrome
  • Apolipoprotein E status

Symptoms

Symptoms of Dementia come on gradually. They often begin mildly, but progress to severe.
Symptoms include:
  • Increasing trouble remembering things, such as:
    • How to get to familiar locations
    • The names of friends, family members
    • Where common objects are usually kept
    • Simple math
    • How to perform usual tasks, such as cooking, dressing, bathing, etc.
  • Trouble concentrating on tasks
  • Trouble completing sentences, due to lost/forgotten words. This progresses to complete inability to speak.
  • Inability to remember the date, time of day, season
  • Mood swings
  • Withdrawal, loss of interest in usual activities
  • Personality changes
  • Slow, shuffling walk
  • Poor coordination
  • Slowness and then loss of purposeful movement

Diagnosis

Doctors diagnose Dementia by:
  • Talking with the patient
  • Observing the patient
  • Performing a physical exam
  • Performing mental status and psychological tests
There are no tests to diagnose Dementia. Tests to rule out other medical conditions may include:
  • Blood tests
  • CT or MRI scans of the head
  • Lumbar puncture – collecting a sample of cerebrospinal fluid by inserting a needle between two vertebrae
  • Electroencephalogram (EEG) – a test that records the brain's activity by measuring electrical currents through the brain

Treatment

Currently there are no treatments to cure dementia and no certain ways to slow its progression. Researchers are studying various drugs to see if they can improve the symptoms of dementia or slow its course.
Medications
Medications being used and studied include:
  • Cholinesterase inhibitors
  • Anti-oxidants (vitamin E)
  • Estrogens
  • Monoamine oxidase inhibitors
  • Anti-inflammatory agents
  • Gingko Biloba (herbal supplement)
Lifestyle Management
Managing the disease includes:
  • Creating an environment in which you can receive the care you need
  • Optimizing your quality of life
  • Keeping yourself safe
  • Helping yourself learn to deal with the frustration of your uncontrollable behavior
  • Providing a calm, quiet, predictable environment
  • Providing appropriate eyewear and hearing aids, easy-to-read clocks and calendars
  • Playing quiet music
  • Light, appropriate exercise to reduce agitation and relieve depression
Psychiatric medications
People with dementia may have psychiatric symptoms. If these symptoms become severe, medication may be needed, such as:
  • Antidepressants
  • Anxiolytics - to treat anxiety
  • Antipsychotics - to treat severe confusion, paranoia, hallucinations
Caregiver Support
Caring for a person with dementia is extremely difficult and exhausting. The primary caregiver needs emotional support, as well as regular respite.

Prevention

There are no guidelines for preventing dementia.