Endocarditis

Endocarditis is an infection of the heart valves and the endocardium. The endocardium is the inner lining of the heart muscle.

Causes

Causes include:
  • Bacterial infection (most common cause)
  • Viral or fungal infection
  • Medical conditions that result in blood clotting too easily (This causes a noninfectious form.)

Risk Factors

A risk factor is something that increases your chance of getting a disease or condition.
  • An artificial heart valve
  • History of endocarditis
  • History of rheumatic fever, which can damage heart valves
  • Heart defects
  • Enlarged heart
  • Mitral valve prolapse
  • History of IV drug use
  • A disorder that causes your blood to clot too easily
  • Autoimmune disorders (such as lupus)
  • Cancer of the gastrointestinal tract or lung
  • Procedures that can lead to bacterial endocarditis, including:
    • Tooth cleaning
    • Tonsillectomy and adenoidectomy
    • Bronchoscopy
    • Surgery on the gastrointestinal, urinary, or respiratory tracts
    • Gallbladder or prostate surgery

Symptoms

Symptoms include:
  • Fever, chills
  • Weakness, low energy
  • Sweatiness, especially at night
  • Shortness of breath
  • Cough
  • Loss of appetite, weight loss
  • Chest pain
  • Abdominal pain
  • Nausea and vomiting
  • Painful red bumps on the fingers and toes
  • Purple dots on the whites of the eyes, under the fingernails, and over the collarbone
  • Painful red patches on the fingers, palms and soles

Diagnosis

The doctor will ask about your symptoms and medical history, and perform a physical exam. The doctor will check your heart for unusual heart sounds (called murmurs).
Tests include:
  • Blood tests – to check for infection
  • Echocardiogram – a test that uses high-frequency sound waves (ultrasound) to examine the size, shape, and motion of the heart

Treatment

Treatment may include: Antibiotics – given through your veins for up to 4-8 weeks.
Surgery – to repair or replace the valve if it is severely damaged.

Prevention

If you are at risk for Endocarditis during certain medical procedures, take antibiotics before the procedure. Medical conditions that require this preventive antibiotic therapy include:
  • Heart defects
  • Artificial heart valves
  • History of endocarditis