Drug Interactions:
Hydralazine

Trade Names
  • Apresoline

Hydralazine causes dilation of the walls of blood vessels and is sometimes used to treat hypertension.

Vitamin B6

Supplementation Likely Helpful

Hydralazine is known to deplete the blood of vitamin B₆. Taking B₆ supplements may prevent or reverse side effects of the medication.^1,2

Coenzyme Q10 (CoQ10)

Supplementation Possibly Helpful

There is some evidence that hydralazine might impair the body's ability to manufacture the substance coenzyme Q₁₀ (CoQ₁₀).³ This suggests (but definitely does not prove) that taking CoQ₁₀ supplements may produce a beneficial effect.

Coleus forskohlii

Theoretical Interaction

The herb Coleus forskohlii relaxes blood vessels and might have unpredictable effects if combined with hydralazine.

Last reviewed March 2002 by Medical Review Board

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